C. Edward S. Mitchell was born July 20, 1943, in Carlisle, Pennsylvania, where his father was attending the Dickinson School of Law. He grew up in Williamsport, attended Williamsport Public Schools, and graduated from Williamsport High School. He graduated from Lafayette College with an AB in 1965. Following college, he served two years active duty as an officer in the United States Army. After separation from active duty in 1967, he attended Dickinson School of Law from which he received a JD Cum Laude in 1970. While at Dickinson, he served as editor-in-chief of the Dickinson Law Review and received the Corpus Juris Secundum Award for the student who contributed the most to overall legal education.

Mr. Mitchell began practice in 1970 in Harrisburg, Pennsylvania, with the firm of Shearer, Mette, and Hoerner. In 1972, he returned to Williamsport and entered practice with his father, J. Neafie Mitchell. On January 1, 1976, his father and he formed Mitchell and Mitchell which is the predecessor of the current firm.

Mr. Mitchell is admitted to practice before all state courts in Pennsylvania, the United States District Court for the Middle District of Pennsylvania, the United States Court of Appeals for the Third Circuit, and the United States Tax Court.

Mr. Mitchell has engaged in an active civil trial practice since August 1972. He has litigated in all counties in North Central Pennsylvania and has handled appeals in state and federal courts to both the Pennsylvania Supreme Court and the United States Supreme Court. For more than twenty years, his practice has been concentrated in defense of professionals in professional liability cases, particularly doctors and lawyers. He also has an active mediation practice.

Mr. Mitchell has been active in professional organizations. He is a member of the Pennsylvania, Federal and American Bar Associations, the Pennsylvania Defense Institute, the Defense Research Institute, and the American Judicature Society. He is a past president of the Lycoming Law Association and is currently Chairman of the Bench Bar Committee. He is a past Chairman of the Middle District Lawyer's Advisory Committee, and a past member of the Middle District Civil Justice Reform Act Committee. He was a delegate to the Third Circuit Judicial Conference in 1991 and 1993. Since 1992 he has been an elected delegate to the PBA House of Delegates. He has been a certified Federal Court Mediator since 1994. He is a Fellow of the American College of Trial Lawyers. He was selected by Philadelphia Magazine as a Pennsylvania Super Lawyer in 2005.

Mr. Mitchell has been active in his community. He has served as a director and officer of the Lycoming United Way, the Lycoming Child Day Care Center, and Christ Episcopal Church. He is a past member of the Williamsport Zoning and Hearing Board and a past chairman of the Williamsport Fire Civil Service Commission. He is a past Trustee of the James V. Brown Library.

Mr. Mitchell's recreation interests include running, hunting, fishing, and other outdoor sports. He served twenty-five years as an officer and director of the Gray's Run Hunting and Fishing Club, including six years as President. He is currently Vice President.

Mr. Mitchell is the father of an adult married son, Jacob N. Mitchell II, an MBA graduate and current investment banker in Charlotte, North Carolina and a former United States Marine Corps Officer. He is the father of an adult married daughter, Caroline Mitchell Hakel, a former live television reporter and United Way executive. He has two granddaughters and two grandsons . His children and grandchildren live in Charlotte and Raleigh, North Carolina.